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CLEC9A

Rat Monoclonal Antibody [Clone 1F6]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Product Details

Synonyms

C type lectin domain family 9, member A; C-type lectin domain family 8 member A; CLEC9A; DNGR1; HEEE9341; PRO34046; UNQ9341; CD370

Positive Control

Mouse spleen.

Known Applications & Suggested Dilutions

Flow Cyt, Western Blot, IF More Details

Flow Cytometry (0.5-1ug/million cells)
Western Blot (1-2ug/ml)
Immunofluorescence (0.5-1ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

RBL-2H3 cells expressing Mouse CLEC9A fused to an HA epitope.

Cellular Localization

Membrane

Species Reactivity

Mouse.

Host / Ig Isotype

Rat / IgG1

Mol. Weight of Antigen

27kDa

Specificity & Comments

This Mab recognizes mouse DNGR-1, which is also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognize a preformed signal exposed on necrotic cells. In peripheral blood, it is highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes.