Home >> Antibodies >> Fibronectin (Fibrin/Heparin-Binding Domain)

Fibronectin (Fibrin/Heparin-Binding Domain)

Mouse Monoclonal Antibody [Clone 616]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Fibronectin Mouse Monoclonal Antibody (616).

SDS-PAGE Analysis Purified Fibronectin Mouse Monoclonal Antibody (616). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Fibronectin Mouse Monoclonal Antibody (616).

SDS-PAGE Analysis Purified Fibronectin Mouse Monoclonal Antibody (616). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Cold insoluble globulin (CIG); FINC; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor (MSF); Ugl-Y3

Positive Control

SW156 cells. Prostate or Kidney.

Known Applications & Suggested Dilutions

Flow Cyt, IF, IHC-P More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Immunogen

High molecular weight proteins secreted by cultivated human fibroblasts

Cellular Localization

Connective tissue matrix

Species Reactivity

Human and Pig.

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

220kDa (monomer); 440kDa (dimer)

Specificity & Comments

Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 29kDa N-terminal fibrin- and heparin-binding domain of fibronectin. It does not cross-react with MMP-2, MMP-9, or TIMP-2. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors.