Home >> Antibodies >> FOLH1 / PSMA (Prostate Epithelial Marker)

FOLH1 / PSMA (Prostate Epithelial Marker)

Recombinant Rabbit Monoclonal Antibody [Clone FOLH1/3149R]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

SDS-PAGE Analysis Purified FOLH1 Rabbit Recombinant Monoclonal Antibody (FOLH1/3149R). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with FOLH1 Rabbit Recombinant Monoclonal Antibody (FOLH1/3149R).

SDS-PAGE Analysis Purified FOLH1 Rabbit Recombinant Monoclonal Antibody (FOLH1/3149R). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with FOLH1 Rabbit Recombinant Monoclonal Antibody (FOLH1/3149R).

Product Details

Synonyms

Cell growth-inhibiting gene 27 protein (GIG27); Folate hydrolase 1 (FOLH1); Folylpoly-gamma-glutamate carboxypeptidase (FGCP); Glutamate carboxylase II (GCPII); Glutamate carboxypeptidase II Membrane glutamate carboxypeptidase N-acetylated-alpha-linked acidic dipeptidase I (NAALAD1 or NAALADase); Prostate-specific membrane antigen (PSM or PSMA); Pteroylpoly-gamma-glutamate carboxypeptidase

Positive Control

LNCap or HepG2 cells. Prostate Carcinoma.

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human FOLH1 protein fragment (around aa 232-433) (exact sequence is proprietary)

Cellular Localization

Cell Surface and Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

100kDa

Specificity & Comments

Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.