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FOXP1 (Transcription Factor)

Recombinant Mouse Monoclonal Antibody [Clone rFOXP1/6902]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with FOXP1 Recombinant Mouse Monoclonal Antibody (rFOXP1/6902) [1ug/ml in PBS] for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2�: HRP-polymer, 30min. DAB, 5min

IHC analysis of formalin-fixed, paraffin-embedded human brain. Negative tissue control. rFOXP1/6902 at 1ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2�: HRP-polymer, 30min. DAB, 5min.

SDS-PAGE Analysis Purified FOXP1 Recombinant Mouse Monoclonal Antibody (rFOXP1/6902). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with FOXP1 Recombinant Mouse Monoclonal Antibody (rFOXP1/6902) [1ug/ml in PBS] for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2�: HRP-polymer, 30min. DAB, 5min

IHC analysis of formalin-fixed, paraffin-embedded human brain. Negative tissue control. rFOXP1/6902 at 1ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2�: HRP-polymer, 30min. DAB, 5min.

SDS-PAGE Analysis Purified FOXP1 Recombinant Mouse Monoclonal Antibody (rFOXP1/6902). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Fork head related protein like B; Forkhead box protein P1 (FOXP1); Glutamine rich factor 1; hFKH1B; HSPC215; QRF1

Positive Control

Human tonsil or colon.

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa350-450) of human FOXP1 protein (exact sequence is proprietary)

Cellular Localization

Nucleus.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

75kDa

Specificity & Comments

Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff ( ��80%) for FOXP1 is needed to achieve high specificity for the ABC subtype.